Abstract Radiation inactivation of enveloped viruses occurs as the result of damages at the molecular level of their genome. The rapidly emerging and ongoing coronavirus disease 2019 (COVID-19) pneumonia pandemic prompted by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now a global health crisis and an economic devastation. The readiness of an active and safe vaccine against the COVID-19 has become a race against time in this unqualified global panic caused by this pandemic. In this review, which we hope will be helpful in the current situation of COVID-19, we analyze the potential use of γ-irradiation to inactivate this virus by damaging at the molecular level its genetic material. This inactivation is a vital step towards the design and development of an urgently needed, effective vaccine against this disease.
【저자키워드】 Vaccine development, SARS-CoV-2 virus, virus inactivation, virus infectivity, virus genome, gamma irradiation, 【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, Vaccine, coronavirus, pandemic, Pneumonia, Genome, virus, Health, inactivation, molecular, disease, Panic, Safe, acute respiratory syndrome, economic devastation, genetic material, effective, caused, virus, occur, γ-irradiation, 【제목키워드】 SARS-CoV-2, Genome, Inactivated vaccine, inactivation, Gamma, virus, Potential,