During flexible fiberoptic bronchoscopy (FOB) the arterial partial pressure of oxygen can drop, increasing the risk for respiratory failure. To avoid desaturation episodes during the procedure several oxygenation strategies have been proposed, including conventional oxygen therapy (COT), high flow nasal cannula (HFNC), continuous positive airway pressure (CPAP) and non-invasive ventilation (NIV). By a review of the current literature, we merely describe the clinical practice of oxygen therapies during FOB. We also conducted a pooled data analysis with respect to oxygenation outcomes, comparing HFNC with COT and NIV, separately. COT showed its benefits in patients undergoing FOB for broncho-alveolar lavage (BAL) or brushing for cytology, in those with peripheral arterial oxyhemoglobin saturation < 93% prior to the procedure or affected by obstructive disorder. HFNC is preferable over COT in patients with mild to moderate acute respiratory failure (ARF) undergoing FOB, by improving oxygen saturation and decreasing the episodes of desaturation. On the opposite, CPAP and NIV guarantee improved oxygenation outcomes as compared to HFNC, and they should be preferred in patients with more severe hypoxemic ARF during FOB. Supplementary Information The online version contains supplementary material available at 10.1186/s12931-021-01846-1.
【저자키워드】 oxygen, non-invasive ventilation, bronchoscopy, Continuous Positive Airway Pressure, High flow nasal cannula, 【초록키워드】 Respiratory failure, risk, nasal, outcome, outcomes, BAL, oxygen saturation, Desaturation, Patient, Data analysis, Oxygen therapy, Mild, HFNC, moderate, Clinical practice, CPAP, Oxygenation, positive airway pressure, supplementary material, disorder, hypoxemic, opposite, NIV, Obstructive, benefit, flexible, affected, conducted, ARF, 【제목키워드】 flexible,