Abstract In December 2019, novel coronavirus pneumonia-19 (COVID-19) was discovered in the viral pneumonia cases that occurred in Wuhan, China, and then quickly spread around the world. This report described the clinical course of two COVID-19 patients and the purpose of the study was to discuss the combination of chest CT and clinical features for diagnosis of COVID-19. The first case was a typical COVID-19 case. A 66-year-old female presented to our hospital with a 3-day history of fever. She had contact with a COVID-19 patient. Chest CT showed a typical COVID-19 appearance. She was diagnosed with COVID-19 by a positive nucleic acid test. The second case was a 50-year-old male with a 2-day history of fever. He denied having been to Wuhan. Chest CT also showed typical features of COVID-19 pneumonia. COVID-19 nucleic acid tests were repeated up to seven times and the results remained controversial. Eventually, he was diagnosed with COVID-19. Our study shows that chest CT has high sensitivity for diagnosis of COVID-19 in clinical practice, particularly when the nucleic acid test is negative. The chest CT should be considered as a diagnostic tool for the COVID-19 screening, comprehensive evaluation, and follow-up and patients would benefit from effective treatments in time.
【저자키워드】 COVID-19, Coronavirus pneumonia, CT, nucleic acid test, 【초록키워드】 Treatment, Pneumonia, hospital, diagnostic, Novel coronavirus, Spread, Viral pneumonia, sensitivity, Clinical course, Chest CT, Fever, Wuhan, male, female, Patient, Follow-up, clinical feature, Clinical practice, Combination, Contact, COVID-19 patient, COVID-19 case, positive, repeated, feature, effective, benefit, Wuhan, China, Seven, described, occurred, remained, diagnosed with COVID-19, diagnosis of COVID-19, two COVID-19 patient, 【제목키워드】 Pneumonia, Diagnosis, 2019 novel coronavirus, Chest CT, clinical feature,