Although the precise pathogenesis of coronavirus disease 2019 (COVID-19) currently remains unknown, its complex nature is gradually being revealed. COVID-19 is a disease caused by the SARS-CoV-2 virus and leads to respiratory dysfunction. Studies on hemostatic parameters have showed that COVID-19 significantly affects the disruption of the coagulation system and may contribute to coagulation and thrombotic events. A relevant cause of hemostasis disorders is inflammation and cytokine storms, which cause, for example, endothelial dysfunction in blood vessels. In order to prevent and treat states of hypercoagulability and thrombosis, the administration of anticoagulants, e.g., heparin, is recommended. The present mini-review describes the relationship between hemostasis and COVID-19, and discusses whether this relationship may cast light on the nature of COVID-19. The present short manuscript also examines the relationship between blood platelets and COVID-19. In addition, the paper explores the potential use of antiplatelet drugs in COVID-19 cases. The studies were identified by searching electronic databases, including PubMed and SCOPUS.
【저자키워드】 COVID-19, cardiovascular disease, Hemostasis, 【초록키워드】 coronavirus disease, Inflammation, Pathogenesis, thrombosis, drug, Endothelial dysfunction, Coagulation, blood vessels, Coagulation system, disease, Thrombotic events, hypercoagulability, Anticoagulants, administration, antiplatelet, COVID-19 cases, Cytokine storms, dysfunction, blood platelet, complex, treat, disorder, manuscript, parameter, Affect, Prevent, caused, example, significantly, addition, contribute, the SARS-CoV-2 virus, 【제목키워드】 piece, puzzle,