Promoting SARS-CoV-2 vaccination has been a global mission since the first vaccines were approved for emergency use. Alongside the excitement following the possibility of eradicating SARS-CoV-2 and ending the COVID-19 pandemic, there has been ample vaccine hesitancy, some due to the abundant reporting of adverse reactions. We report here that the occurrence of BNT162b2 vaccine adverse reactions is associated with enhanced antibody response. We found a statistically significant correlation between having an adverse reaction, whether local or systemic, and higher antibody levels. No sex difference was observed in antibody levels. However, as was recently reported, the antibody response was found to be lower among older vaccinees. The demonstration of a clear correlation between adverse reactions and antibody levels may help reduce vaccination hesitancy by reassuring that the presence of such reactions is an indication of a well-functioning immune system.
【저자키워드】 COVID-19, antibodies, SARS-CoV-2, Vaccine, BNT162b2, Adverse reactions, Vaccination hesitancy, 【초록키워드】 vaccination, antibody, COVID-19 pandemic, Antibody Response, Local, immune system, Vaccine hesitancy, correlation, Sex difference, SARS-CoV-2 vaccination, Emergency use, Adverse reaction, Older, reaction, help, vaccinees, excitement, Occurrence, reported, approved, reduce, statistically significant, the antibody response, Promoting, of BNT162b2, 【제목키워드】 response, SARS-CoV-2 IgG, Adverse, reaction, enhanced, of BNT162b2,