Background. The early effects of coronavirus disease 2019 (COVID-19) on transplantation are dramatic: >75% of kidney and liver programs are either suspended or operating under major restrictions. To resume transplantation, it is important to understand the prevalence of COVID-19 among transplant recipients, donors, and healthcare workers (HCWs) and its associated mortality. Methods. To investigate this, we studied severe acute respiratory syndrome coronavirus 2 diagnostic test results among patients with end-stage renal disease or kidney transplants from the Johns Hopkins Health System (n = 235), and screening test results from deceased donors from the Southwest Transplant Alliance Organ Procurement Organization (n = 27), and donors, candidates, and HCWs from the National Kidney Registry and Viracor-Eurofins (n = 253) between February 23 and April 15, 2020. Results. We found low rates of COVID-19 among donors and HCWs (0%–1%) who were screened, higher rates of diagnostic tests among patients with end-stage renal disease or kidney transplant (17%–20%), and considerable mortality (7%–13%) among those who tested positive. Conclusions. These findings suggest the threat of COVID-19 for the transplant population is significant and ongoing data collection and reporting is critical to inform transplant practices during and after the pandemic.
【초록키워드】 COVID-19, coronavirus disease, coronavirus, pandemic, Mortality, diagnostic test, diagnostic, healthcare worker, organization, kidney, Transplant, HCWs, Patient, End-stage renal disease, donors, registry, Critical, liver, kidney transplant, Donor, screening test, Deceased, HCW, Candidates, acute respiratory syndrome, recipients, positive, Effect, System, tested, screened, Alliance, Johns Hopkin, prevalence of COVID-19, 【제목키워드】 COVID-19, Testing, experience, transplantation,