Abstract Objective To identify the effectiveness of a personnel protection strategy in protection of healthcare workers from SARS-CoV-2 infection. Design During the COVID-19 pandemic, 943 healthcare staff sent from Guangzhou to Wuhan to care for patients with suspected/confirmed COVID-19 received infection precaution training before their mission and were equipped with Level 2/3 personal protective equipment (PPE), in accordance with guidelines from the National Health Commission of China. We conducted a serological survey on the cumulative attack rate of SARS-CoV-2 among the healthcare workers sent to Wuhan and compared the seropositive rate to that in local healthcare workers from Wuhan and Jingzhou. Results Serial tests for SARS-CoV-2 RNA and tests for SARS-CoV-2 immunoglobulin M and G after the 6-8 week mission revealed a zero cumulative attack rate. Among the local healthcare workers in Wuhan and Jingzhou of Hubei Province, 2.5% (113 out of 4495) and 0.32% (10 out of 3091) had RT-PCR confirmed COVID-19, respectively. The seropositivity for SARS-CoV-2 antibodies (IgG, IgM, or both IgG/IgM positive) was 3.4% (53 out of 1571) in local healthcare workers from Wuhan with Level 2/3 PPE working in isolation areas and 5.4% (126 out of 2336) in healthcare staff with Level 1 PPE working in non-isolation medical areas, respectively. Conclusions and relevance Our study confirmed that adequate training/PPE can protect medical personnel against SARS-CoV-2.
【저자키워드】 COVID-19, Healthcare workers, Personal protective equipment (PPE), 【초록키워드】 SARS-CoV-2, IgG, IgM, Personal protective equipment, SARS-COV-2 infection, COVID-19 pandemic, Infection, Local, RT-PCR, healthcare worker, China, SARS-CoV-2 antibody, Immunoglobulin, attack rate, healthcare, Wuhan, Patient, Effectiveness, Isolation, PPE, SARS-CoV-2 RNA, Care, seropositive, Guangzhou, level 1, cumulative, positive, National Health Commission, serological survey, objective, PROTECT, Result, identify, conducted, Level, 【제목키워드】 healthcare worker, Wuhan, COVID-19 epidemic,