Arizona’s COVID-19 and Pets Program is a prospective surveillance study being conducted to characterize how SARS-CoV-2 impacts companion animals living in households with SARS-CoV-2-positive individuals. Among the enrolled pets, we identified a SARS-CoV-2-infected cat and dog from the same household; both animals were asymptomatic but had close contact with the symptomatic and SARS-CoV-2-positive owner. Whole genome sequencing of animal and owner specimens revealed identical viral genomes of the B.1.575 lineage, suggesting zoonotic transmission of SARS-CoV-2 from human to at least one pet. This is the first report of the B.1.575 lineage in companion animals. Genetically linking SARS-CoV-2 between people and animals, and tracking changes in SARS-CoV-2 genomes is essential to detect any cross-species SARS-CoV-2 transmission that may lead to more transmissible or severe variants that can affect humans. Surveillance studies, including genomic analyses of owner and pet specimens, are needed to further our understanding of how SARS-CoV-2 impacts companion animals. Highlights • Two companion animals from the same household tested positive for SARS-CoV-2. • Sequencing of the cat, dog, and pet owner samples revealed identical viral genomes. • Phylogenetic analysis shows that the viral genomes fall into a locally circulating clade of B.1.575. • This is the first known report of the B.1.575 lineage in companion animals. • Evidence of viral transmission from a pet owner to at least one pet in the same household was identified through genomic sequencing.
【저자키워드】 SARS-CoV-2, pets, one health, companion animals, genomic sequencing, RT-PCR, Real-time Polymerase Chain Reaction, 【초록키워드】 COVID-19, variant, SARS-CoV-2 transmission, Whole genome sequencing, Asymptomatic, Surveillance, SARS-CoV-2 genome, symptomatic, humans, Impact, Program, Lineage, clade, viral genomes, Viral transmission, genomic, specimens, Analysis, viral genome, close contact, evidence of, specimen, circulating, zoonotic transmission, positive, SARS-CoV-2-positive individuals, Affect, enrolled, tested, detect, conducted, changes in, 【제목키워드】 Cluster, SARS-CoV-2 disease,