Du, Ren, et al. recently showed in a Plasmodium berghei ANKA (PbA) experimental malaria model that phosphatase of regenerating liver 2 (PRL2) regulates neutrophil extracellular traps (NETs) in severe malaria (SM)-related acute lung injury (ALI). PRL2 deficiency caused SM with ALI in a mouse model by increasing NETs in pulmonary tissue; hydroxychloroquine (HCQ) may ameliorate this.
All Keywords
【저자키워드】 acute lung injury, neutrophil extracellular traps (NETs), murine malaria,
【저자키워드】 acute lung injury, neutrophil extracellular traps (NETs), murine malaria,