The coronavirus E protein is a small membrane protein that has an important role in the assembly of virions. Recent studies have indicated that the E protein has functions during infection beyond assembly, including in virus egress and in the host stress response. Additionally, the E protein has ion channel activity, interacts with host proteins, and may have multiple membrane topologies. The goal of this review is to highlight the properties and functions of the E protein, and speculate on how they may be related.
All Keywords
【저자키워드】 envelope protein, ion channel, coronavirus assembly, Golgi complex, membrane protein topology, 【초록키워드】 coronavirus, Stress, Infection, virus, E protein, membrane protein, membrane, function, assembly, host proteins, virions, Host, recent, highlight, related, indicated, interact, topologies,
【저자키워드】 envelope protein, ion channel, coronavirus assembly, Golgi complex, membrane protein topology, 【초록키워드】 coronavirus, Stress, Infection, virus, E protein, membrane protein, membrane, function, assembly, host proteins, virions, Host, recent, highlight, related, indicated, interact, topologies,