Avian infectious bronchitis virus (IBV) is an important gammacoronavirus. The virus is highly contagious, can infect chickens of all ages, and causes considerable economic losses in the poultry industry worldwide. In the last few decades, numerous studies have been published regarding pathogenicity, vaccination, and host immunity-virus interaction. In particular, innate immunity serves as the first line of defense against invasive pathogens and plays an important role in the pathogenetic process of IBV infection. This review focuses on fundamental aspects of host innate immune responses after IBV infection, including identification of conserved viral structures and different components of host with antiviral activity, which could provide useful information for novel vaccine development, vaccination strategies, and intervention programs.
【저자키워드】 Innate immunity, interferons, chicken, pattern recognition receptor, avian infectious bronchitis virus, 【초록키워드】 Structure, Vaccine development, vaccination, innate immune response, Intervention, antiviral activity, virus, Vaccination strategies, pathogenicity, information, Interaction, IBV infection, Infectious Bronchitis Virus, component, contagious, Defense, infect, Host, IBV, conserved, cause, invasive pathogen, 【제목키워드】 response, Innate, focus,