Objective: The recent outbreak of Novel Coronavirus Disease (COVID-19) is reminiscent of the SARS outbreak in 2003. We aim to compare the severity and mortality between male and female patients with COVID-19 or SARS. Study Design and Setting: We extracted the data from: (1) a case series of 43 hospitalized patients we treated, (2) a public data set of the first 37 cases of patients who died of COVID-19 and 1,019 patients who survived in China, and (3) data of 524 patients with SARS, including 139 deaths, from Beijing in early 2003. Results: Older age and a high number of comorbidities were associated with higher severity and mortality in patients with both COVID-19 and SARS. Age was comparable between men and women in all data sets. In the case series, however, men’s cases tended to be more serious than women’s ( P = 0.035). In the public data set, the number of men who died from COVID-19 is 2.4 times that of women (70.3 vs. 29.7%, P = 0.016). In SARS patients, the gender role in mortality was also observed. The percentage of males were higher in the deceased group than in the survived group ( P = 0.015). Conclusion: While men and women have the same prevalence, men with COVID-19 are more at risk for worse outcomes and death, independent of age.
【저자키워드】 COVID-19, SARS-CoV-2, Mortality, SARS, Gender, morbidity, male, female, 【초록키워드】 coronavirus disease, severity, Comorbidities, risk, outcome, novel coronavirus disease, Novel coronavirus, Prevalence, China, Case series, outbreak, Patient, Older age, death, age, women, novel, Deceased, deaths, independent of, data set, data sets, gender role, Beijing, while, SARS patients, men, independent, patients with SARS, died, case sery, treated, hospitalized patient, comparable, survived, female patient, men and women, number of comorbidity, patients who survived, with COVID-19, 【제목키워드】 focus, difference,