Abstract New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS‐CoV‐2, which are all Alpha‐ and Beta‐coronavirus . In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose‐dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid. Our results indicated that nanoGO material revealed different levels of antiviral activity against different viruses.
【저자키워드】 Coronaviruses, antiviral activity, nano‐graphene oxide, 【초록키워드】 viruses, coronavirus, therapy, Infectious disease, virus, SARS‐CoV‐2, serum, Epidemic, virus inhibition, Bovine coronavirus, diarrhoea, acute respiratory syndrome, PEDV, indicated, investigated, evaluated, inhibited, New, utilised, 【제목키워드】 Betacoronavirus, Alpha, application, nontoxic,