Background Peru is the country with the world’s highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described. Methods Retrospective, single-center cohort study including 1537 adult patients hospitalized with a diagnosis of SARS-CoV-2 pneumonia between May 2020 and August 2020 at a national hospital in Lima, Peru. The primary outcome measure was in-hospital mortality. Results In-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multivariate model adjusted for age, hypertension, diabetes mellitus, and corticosteroid use demonstrated that in-hospital mortality was associated with greater age (RR: 2.01, 95%CI: 1.59–2.52) and a higher level of oxygen requirement (RR: 2.77, 95%CI: 2.13–3.62). Conclusions: In-hospital mortality among COVID-19 patients in Peru is high and is associated with greater age and higher oxygen requirements.
【초록키워드】 Corticosteroid, COVID-19, Mortality, Pneumonia, hospital, Diabetes Mellitus, inflammatory markers, C-reactive protein, D-dimer, ferritin, hypertension, lactate dehydrogenase, cohort study, age, in-hospital mortality, association, leukocytes, COVID-19 patient, death rate, Oxygen requirements, multivariate model, primary outcome measure, single-center, increased mortality, National, Oxygen requirement, country, males, Result, greater, highest, described, adjusted, demonstrated, diagnosis of SARS-CoV-2, patients hospitalized, patients with COVID-19, 【제목키워드】 Hospitalized, Mortality, Pneumonia, retrospective cohort study, patients with COVID-19,