Objectives The purpose is to assess the ability of low-dose CT (LDCT) to determine lung involvement in SARS-CoV-2 pneumonia and to describe a COVID19-LDCT severity score. Materials and methods Patients with SARS-CoV-2 infection confirmed by RT-PCR were retrospectively analysed. Clinical data, the National Early Warning Score (NEWS) and imaging features were recorded. Lung features included ground-glass opacities (GGO), areas of consolidation and crazy paving patterns. The COVID19-LDCT score was calculated by summing the score of each segment from 0 (no involvement) to 10 (severe impairment). Univariate analysis was performed to explore predictive factor of high COVID19-LDCT score. The nonparametric Mann-Whitney test was used to compare groups and a Spearman correlation used with p<0.05 for significance. Results Eighty patients with positive RT-PCR were analysed. The mean age was 55 years ± 16, with 42 males (53%). The most frequent symptoms were fever (60/80, 75%) and cough (59/80, 74%), the mean NEWS was 1.7±2.3. All LDCT could be analysed and 23/80 (28%) were normal. The major imaging finding was GGOs in 56 cases (67%). The COVID19-LDCT score (mean value = 19±29) was correlated with NEWS (r = 0.48, p<0.0001). No symptoms were risk factor to have pulmonary involvement. Univariate analysis shown that dyspnea, high respiratory rate, hypertension and diabetes are associated to a COVID19-LDCT score superior to 50. Conclusions COVID19-LDCT score did correlate with NEWS. It was significantly different in the clinical low-risk and high-risk groups. Further work is needed to validate the COVID19-LDCT score against patient prognosis.
【초록키워드】 Prognosis, SARS-COV-2 infection, severity, lung involvement, Symptom, risk factor, cough, RT-PCR, hypertension, ground-glass opacity, clinical, low-dose, Fever, Dyspnea, male, Patient, age, GGO, SARS-CoV-2 pneumonia, correlation, group, consolidation, score, positive RT-PCR, Analysis, respiratory rate, Predictive, no symptom, mean value, pulmonary involvement, Mann-Whitney test, material, impairment, Spearman, objective, feature, Result, shown, was used, significantly, was performed, analysed, calculated, determine, correlated, groups, the mean, diabete, were recorded, 【제목키워드】 lung involvement, Chest CT, SARS-CoV-2 pneumonia, Quantitative, diagnosing,