ABSTRACT Objective: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. These cases are reported as presenting the Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19. In this study, we describe with parental permission a case of MIS-C in an infant with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Case description: A seven-month-old infant, with SARS-CoV-2 infection and a history of extreme preterm birth and very low weight at birth, with an initial course of mild respiratory symptoms and abrupt progression to vasoplegic shock, myocarditis and hyperinflammation syndrome, shown by high levels of troponin I, ferritin, CRP, D-dimer and hypoalbuminemia. Despite the intensive care provided, the child developed multiple organ dysfunction and died. Comments: Patients with a history of extreme prematurity may present with MIS-C in the presence of COVID-19 and are a group of special concern.
【저자키워드】 COVID-19, multiple organ failure, Intensive care units, Pediatric, Insuficiência de múltiplos órgãos, Unidades de terapia intensiva pediátrica, 【초록키워드】 SARS-CoV-2, coronavirus, intensive care, SARS-COV-2 infection, children, Infection, inflammatory markers, CRP, D-dimer, ferritin, progression, MIS-C, Shock, Preterm birth, myocarditis, hyperinflammation, troponin I, multiple organ dysfunction, Inflammatory, Multiorgan dysfunction, acute respiratory syndrome, syndrome, initial, extreme, Course, shown, died, reported, elevated, provided, presenting, parental, mild respiratory symptom, with COVID-19,