Introduction Coinfection with severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) and another virus may influence the clinical trajectory of emergency department (ED) patients. However, little empirical data exists on the clinical outcomes of coinfection with SARS-CoV-2 Methods In this retrospective cohort analysis, we included adults presenting to the ED with confirmed, symptomatic coronavirus 2019 who also underwent testing for additional viral pathogens within 24 hours. To investigate the association between coinfection status with each of the outcomes, we performed logistic regression. Results Of 6,913 ED patients, 5.7% had coinfection. Coinfected individuals were less likely to experience index visit or 30-day hospitalization (odds ratio [OR] 0.57; 95% confidence interval [CI], 0.36–0.90 and OR 0.39; 95% CI, 0.25–0.62, respectively). Conclusion Coinfection is relatively uncommon in symptomatic ED patients with SARS-CoV-2 and the clinical short- and long-term outcomes are more favorable in coinfected individuals.
【초록키워드】 SARS-CoV-2, Hospitalization, outcome, virus, Clinical outcome, outcomes, Coinfection, symptomatic, Logistic regression, trajectory, Coronavirus 2019, patients, association, Analysis, Odds ratio, 24 hours, 95% CI, 95% confidence interval, individual, retrospective cohort, viral pathogen, Result, performed, less, individuals, presenting, patients with SARS-CoV-2, 【제목키워드】 SARS-CoV-2, Coinfection, Emergency, Department, Improved,