The number of people vaccinated against COVID-19 increases worldwide every day; however, it is important to study the risk of breakthrough infections in vaccinated individuals at high risk of exposure such as healthcare personnel (HCP). A systematic literature review (SLR) applying the PRISMA declaration and the PECOS format using the following entry terms was used: “Health Personnel OR Healthcare Worker OR Healthcare Provider OR Healthcare Personnel AND breakthrough OR infection after vaccine*”. The research was carried out utilizing the following databases: SCOPUS, PubMed, Embase, and Web of Sciences. An overall very low incidence of post-vaccination breakthrough infections was found, ranging from 0.011 to 0.001 (per 100 individuals at risk). Our findings further support the published high effectiveness rates of mRNA vaccines in preventing SARS-CoV-2 infections among fully vaccinated HCP. Additional studies are needed to define the duration of the vaccine-induced protection among HCP.
【저자키워드】 COVID-19, SARS-CoV-2, vaccination, pandemic, mRNA-1273, BNT162b2, asymptomatic infection, healthcare personnel, Post-vaccination, TAK-919, 【초록키워드】 mRNA vaccine, SARS-COV-2 infection, Infection, risk, Research, Effectiveness, Breakthrough infection, incidence, high risk, Support, literature review, individual, worker, vaccinated individual, hcp, carried, increase, Web, to define, vaccinated against COVID-19, 【제목키워드】 review, mRNA,