Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomodulator hormone with established effectiveness against various upper respiratory infections. Vitamin D can stall hyper-inflammatory responses and expedite healing process of the affected areas, primarily in the lung tissue. Thus, there are ecological and mechanistic reasons to promote exploration of vitamin D action in COVID-19 patients. As no curative drugs are available currently for COVID-19, we feel that the potential of vitamin D to alter the course of disease severity needs to be investigated. Clinical studies may be undertaken to address the value of vitamin D supplementation in deficient, high-risk COVID-19 patients.
【초록키워드】 COVID-19, SARS-CoV-2, coronavirus, pandemic, Mortality, Vitamin D, disease severity, drug, virus, immunomodulator, infections, clinical, Effectiveness, COVID-19 patients, acute respiratory distress, Vitamin D supplementation, acute respiratory syndrome, hyper-inflammatory response, syndrome, lung tissue, public health threat, Alter, upper respiratory, Course, affected, investigated, promote, ecological, curative, 【제목키워드】 COVID-19, deficiency,