Patients with novel coronavirus disease 2019 (COVID-19) experience various degrees of liver function abnormalities. Liver injury requires extensive work-up and continuous surveillance and can be multifactorial and heterogeneous in nature. In the context of COVID-19, clinicians will have to determine whether liver injury is related to an underlying liver disease, drugs used for the treatment of COVID-19, direct effect of the virus, or a complicated disease course. Recent studies proposed several theories on potential mechanisms of liver injury in these patients. This review summarizes current evidence related to hepatobiliary complications in COVID-19, provides an overview of the available case series and critically elucidates the proposed mechanisms and provides recommendations for clinicians.
【저자키워드】 COVID-19, Cytokine storm, SARS-CoV2, lymphopenia, Liver injury, Liver function test, cholangiocytes, 【초록키워드】 Treatment, drug, novel coronavirus disease, virus, Surveillance, Liver function, Complication, patients, mechanism, Evidence, Injury, Liver disease, Clinicians, potential mechanism, clinician, disease course, Abnormalities, heterogeneous, multifactorial, recommendation, recent, case sery, provide, determine, 【제목키워드】 Evidence, Injury,