This study examined the neuropsychiatric sequelae of acutely ill patients with coronavirus disease 2019 (COVID-19) infection who received treatment in hospital isolation wards during the COVID-19 pandemic. Ten COVID-19 patients who received treatment in various hospitals in Chongqing, China; 10 age- and gender-matched psychiatric patients; and 10 healthy control participants residing in the same city were recruited. All participants completed a survey that collected information on demographic data, physical symptoms in the past 14 days and psychological parameters. Face-to-face interviews with COVID-19 patients were also performed using semi-structured questions. Among the COVID-19 patients, 40% had abnormal findings on the chest computed topography scan, 20% had dysosmia, 10% had dysgeusia, and 80% had repeated positivity on COVID-19 reverse-transcription polymerase chain reaction testing. COVID-19 and psychiatric patients were significantly more worried about their health than healthy controls ( p = 0.019). A greater proportion of COVID-19 patients experienced impulsivity ( p = 0.016) and insomnia ( p = 0.039) than psychiatric patients and healthy controls. COVID-19 patients reported a higher psychological impact of the outbreak than psychiatric patients and healthy controls, with half of them having clinically significant symptoms of posttraumatic stress disorder. COVID-19 and psychiatric patients had higher levels of depression, anxiety and stress than healthy controls. Three themes emerged from the interviews with COVID-19 patients: (i) The emotions experienced by patients after COVID-19 infection (i.e., shock, fear, despair, hope, and boredom); (ii) the external factors that affected patients’ mood (i.e., discrimination, medical expenses, care by healthcare workers); and (iii) coping and self-help behavior (i.e., distraction, problem-solving and online support). The future direction in COVID-19 management involves the development of a holistic inpatient service to promote immune and psychological resilience.
【저자키워드】 Diseases, Depression, Psychiatric disorders, 【초록키워드】 COVID-19, Treatment, coronavirus disease, Anxiety, Stress, COVID-19 pandemic, hospital, Infection, Symptom, immune, Shock, Health, COVID-19 infection, outbreak, management, healthcare, psychological Impact, Chest, Patient, Isolation, Neuropsychiatric, age, Insomnia, Psychological, information, Care, parameters, COVID-19 patients, COVID-19 patient, Support, Posttraumatic Stress, Psychiatric, Factor, healthy control, demographic data, participant, healthy controls, psychological resilience, disorder, repeated, Chongqing, Physical symptom, polymerase chain, greater, performed, affected, collected, examined, significantly more, proportion, recruited, reported, clinically, promote, acutely ill patient, All participant, with COVID-19, 【제목키워드】 COVID-19, Isolation, Neuropsychiatric, Quantitative, Inpatient,