Abstract Coronavirus disease 2019 (COVID‐19) is an important health problem that has a serious adverse impact on the global economy and healthcare systems. The virus is not only involved in the respiratory system, but also causes other systemic effects as well as several gastrointestinal and liver issues. Evidence has shown direct viral invasion into the gastrointestinal tissue and supporting vascular network, causing various manifestations such as diarrhea, nausea, gastrointestinal bleeding, and abnormal liver function tests. The degree of gastrointestinal injury, especially in terms of liver involvement, is correlated with disease severity. There is no specific treatment for gastrointestinal involvement, and the symptoms can be managed with supportive therapy. Moreover, increased liver decompensation and mortality can be found in COVID‐19‐infected patients with coexisting liver disease. As the virus can be identified in gastrointestinal contents, endoscopic procedures during the pandemic should be carefully selected and proper protection strategies should be encouraged to prevent viral transmission. Patients with coronavirus disease 2019 typically present with fever and respiratory symptoms; however, gastrointestinal symptoms and liver issues have also been reported. Endoscopic procedures during the pandemic should be carefully selected and proper protection strategies should be encouraged to prevent viral transmission.
【저자키워드】 severe acute respiratory syndrome coronavirus 2, Coronavirus disease 2019, diarrhea, Gastrointestinal, liver, angiotensin‐converting enzyme 2 receptor, 【초록키워드】 coronavirus disease, pandemic, therapy, Mortality, disease severity, Symptom, virus, COVID‐19, Health, Fever, Patient, bleeding, liver function tests, Viral transmission, Respiratory system, Injury, Liver disease, manifestation, Healthcare systems, Vascular, nausea, specific treatment, viral invasion, adverse impact, Gastrointestinal symptom, Prevent, gastrointestinal involvement, selected, shown, involved, reported, correlated, cause, gastrointestinal tissue, systemic effect, 【제목키워드】 manifestation,