Objectives : The aim of this study was to assess the diagnostic role of eosinophils count in COVID-19 patients. Methods : Retrospective analysis of patients admitted to our hospital with suspicion of COVID-19. Demographic, clinical and laboratory data were collected on admission. Eosinopenia was defined as eosinophils < 100 cells/mm 3 . The outcomes of this study were the association between eosinophils count on admission and positive real-time reverse transcription polymerase chain reaction (rRT-PCR) test and with suggestive chest computerized tomography (CT) of COVID-19 pneumonia. Results : A total of 174 patients was studied. Of those, 54% had positive rRT-PCR for SARS-CoV-2. A chest CT-scan was performed in 145 patients; 71% showed suggestive findings of COVID-19. Eosinophils on admission had a high predictive accuracy for positive rRT-PCR and suggestive chest CT-scan (area under the receiver operating characteristic—ROC curve, 0.84 (95% CIs 0.78–0.90) and 0.84 (95% CIs 0.77–0.91), respectively). Eosinopenia and high LDH were independent predictors of positive rRT-PCR, whereas eosinopenia, high body mass index and hypertension were predictors for suggestive CT-scan findings. Conclusions : Eosinopenia on admission could predict positive rRT-PCR test or suggestive chest CT-scan for COVID-19. This laboratory finding could help to identify patients at high-risk of COVID-19 in the setting where gold standard diagnostic methods are not available.
【저자키워드】 COVID-19, coronavirus, eosinophils, chest CT imaging, reverse transcription polymerase, 【초록키워드】 SARS-CoV-2, Pneumonia, hospital, diagnostic, LDH, outcome, hypertension, eosinophil, Laboratory, Computerized tomography, rRT-PCR, body mass index, Accuracy, Chest, Patient, reverse transcription, predictor, demographic, Admission, predict, CT-scan, COVID-19 patients, Diagnostic method, association, Eosinopenia, Analysis, Predictive, gold standard, laboratory data, help, positive, chest CT-scan, rRT-PCR test, objective, polymerase chain, Result, defined, identify, collected, was performed, independent predictor, 【제목키워드】 Eosinopenia,