Abstract Introduction: Hyaluronic acid injections is relatively safe with little risk of complications. Although herpes reactivation after the injection of hyaluronic acid is rare, it produces quite a huge pressure and panic on patients. Quite a lot cosmetic practitioners have no awareness of preventing, diagnosing, and giving correct treatment in time due to lack of experience. Patient concerns: A 24-year-old woman presented with erythema, crusted papules, pain and swelling on the nose after receiving the injection of hyaluronic acid. A swab of the discharge fluid was obtained for bacterial and viral culture, showing positive for herpes simplex virus. Diagnosis: The patient was diagnosed as herpes reactivation after the injection of hyaluronic acid. Interventions: The patient underwent antiviral therapy with acyclovir 400 mg, 3 times daily for seven days. Outcomes: After a week of antiviral treatment, the clinical signs improved. Conclusion: Herpes reactivation after the injection of hyaluronic acid is quite rare but needed sufficient attention of cosmetic practitioners to make the proper diagnosis, prevention and treatment.
【저자키워드】 Hyaluronic acid, cosmetic injection, herpes reactivation,