New developments in the pharmacotherapy of neuropathic chronic pelvic pain

Advancements in further understanding the pathophysiology of chronic pelvic pain syndromes continue to direct therapy. The mechanisms of chronic pelvic pain are often multifactorial and therefore require a multidisciplinary approach. The final treatment plan is often an accumulation of organ-specific treatment and chronic pain medications directed to the CNS and PNS. This article is a review of commonly used medications for chronic pelvic neuropathic pain disorders as well as an introduction to recent innovative developments in pain medicine. Lay abstract Chronic nonmalignant pain, regardless of the cause, is a difficult disease to treat. While currently managed with a variety of medications, few alone are clinically effective. Often, many medications and therapies are used in combination to provide the maximum benefit for the patient. Several new medications listed below are being developed and applied to chronic pelvic pain.