Objectives This study evaluated the clinical manifestation of COVID-19 and adverse outcomes in patients with comorbidities (outcome: death). Methods A comparative follow-up investigation involving 148 confirmed cases of COVID-19 was performed for a month (between April and May 2020) at Qaha Hospital to describe the clinical characteristics and outcomes resulting from comorbidities. Participants were divided into two clusters based on the presence of comorbidities. Group I comprised cases with comorbidities, and Group II included subjects without comorbidity. Survival distributions were outlined for the group with comorbidities after the follow-up period. Results Fever (74.3%), headache (78.4%), cough (78.4%), sore throat (78.4%), fatigue (78.4%), and shortness of breath (86.5%) were the most prevalent symptoms observed in COVID-19 patients with comorbidities. Such patients also suffered from acute respiratory distress syndrome (37.8%) and pneumonia three times more than patients without comorbidities. The survival distributions were statistically significant (chi-square = 26.06, p ≤ 0.001). Conclusion Multiple comorbidities in COVID-19 patients are linked to severe clinical symptoms, disease complications, and critical disease progression. The presence of one or more comorbidities worsened the survival rate of patients.
【초록키워드】 COVID-19, Clinical symptoms, fatigue, Clinical characteristics, Pneumonia, Comorbidities, Comorbidity, Symptom, progression, outcome, cough, headache, adverse outcome, survival, Patient, death, Cluster, complications, Follow-up, survival rate, group, distribution, disease, patients, Critical disease, acute respiratory distress, COVID-19 patient, Shortness of breath, sore throat, confirmed case, follow-up period, subject, syndrome, participant, Multiple, objective, prevalent, Result, resulting, evaluated, was performed, suffered, statistically significant, outlined, patients with comorbidity, presence of comorbidities, worsened, 【제목키워드】 COVID-19, Impact,