This cross-sectional study describes the clinical characteristics and outcomes of patients with COVID-19 infection in Gabon from March to June 2020. Key Points Question What were the epidemiologic and clinical aspects of patients with COVID-19 infection in the Armed Forces Hospital in Libreville, Gabon, from March to June 2020? Findings In this cross-sectional study of 837 patients with COVID-19 in Gabon, 63% had no symptoms. Severity of disease and mortality were associated with advanced age and advanced stage of lung damage. Meaning Findings from this observational study provide preliminary data for use in future epidemiologic studies of COVID-19 in Gabon. Importance Since the emergence of COVID-19 in central China, sub-Saharan African countries, with the exception of South Africa, have been relatively spared during the COVID-19 pandemic. Consequently, few descriptive studies from this region are available. Objective To describe the clinical characteristics and outcomes of patients with COVID-19 infection in Gabon, from March to June 2020. Design, Setting, and Participants A single-center, cross-sectional study of 837 patients with COVID-19 was conducted from March to June 2020 in the Armed Forces Hospital in Libreville, Gabon. Main Outcomes and Measures Demographic and clinical characteristics and imaging findings of hospitalized patients with COVID-19. Results Of the 837 patients enrolled, 572 (68.3%) were men, and 264 (31.5%) were women (male to female ratio, 2:1); the median (interquartile range [IQR]) age was 35 (30-45) years (mean [SD] age, 38.0 [12.2] years. The mortality rate associated with COVID-19 was low (1.4%). Of these 837 patients, 524 (62.6%) were categorized as having no symptoms, 282 (33.7%) as having mild symptoms, and 31 (3.7%) as having severe symptoms. Patients with severe symptoms were older (mean [SD] age, 46.1 [14.7] years) than patients with mild symptoms (mean [SD] age, 41.3 [12.5] years) and those with no symptoms (mean [SD] age, 35.7 [11.3] years) (Kruskal-Wallis χ 2 2 = 53.5; P < .001). History of diabetes was the principal risk factor associated with both severe symptoms in 5 of 31 patients (16.1%) and mild symptoms in 11 of 282 (3.9%) compared with no symptoms in 5 of 524 (0.9%) (Pearson χ 2 2 = 30.9; P < .001). Patients with severe symptoms and a fatal outcome were older (mean [SD] age, 53.4 [15.1] years) than survivors (mean [SD] age, 41.5 [12.9] years) ( t 20.83 = 2.2; P = .03). Conclusions and Relevance In this single-center, cross-sectional study in Libreville, Gabon, the mortality rate associated with COVID-19 infection from March to June 2020 was low, and patients who died of COVID-19 infection were younger on average than reported elsewhere, possibly reflecting a smaller elderly population in Gabon.
【초록키워드】 COVID-19, Mortality, Clinical characteristics, cross-sectional, COVID-19 pandemic, Infection, outcome, risk factor, Symptoms, China, South Africa, COVID-19 infection, African, male, female, Patient, age, mortality rate, women, demographic, disease, patients, mild symptoms, Gabon, lung damage, no symptoms, interquartile range, history, Older, no symptom, Mild symptom, average, severe symptoms, advanced age, measure, single-center, participant, Preliminary data, finding, force, Pearson, Kruskal-Wallis, survivor, men, objective, setting, Result, enrolled, died, reported, conducted, hospitalized patient, had no, Importance, diabete, severe symptom, patients with COVID-19, Point, Relevance, the median, with COVID-19, 【제목키워드】 COVID-19, clinical, demographic, Gabon,