Objectives: To present the temporal changes of CT manifestations in COVID-19 patients from a single fangcang shelter hospital and to facilitate the understanding of the disease course. Materials and Methods: This retrospective study included 98 patients (males: females, 43:55, mean year, 49±12 years) with confirmed COVID-19 at Jianghan fangcang shelter hospital admitted between Feb 05, 2020, and Feb 09, 2020, who had initial chest CTs at our hospital. Radiographic features and CT scores were analyzed. Results: A total of 267 CT scans of 98 patients were evaluated. Our study showed a high median total CT score of 7 within the first week from symptom onset, peaked in the 2 nd week at 10, followed by persistently high levels of CT score with 9.5, 7 and 7 for the week 3, 4, and >4, respectively, and a prolonged median disease course (30 days, the median interval between the onset of initial symptoms and discharge). Ground-glass opacity (GGO) (58%, 41/71) was the earliest and most frequent finding in week 1. Consolidation (26%, 14/53) and mixed pattern (40%, 21/53) were predominant patterns in 2 nd week. GGO and reticular were the main patterns of later phase CT scans in patients with relatively advanced diseases who had longer illness duration (≥4 weeks). Among the 94 CT abnormalities obtained within 3 days from the twice RT-PCR test turned negative, the mixed pattern was mainly presented in patients with disease duration of 2-3 weeks, for GGO and reticular were common during the whole course. Conclusion: Discharged patients from fangcang shelter hospital demonstrated a high extent of lung abnormalities on CT within the first week from symptom onset, peaked at 2 nd week, followed by persistence of high levels and a prolonged median disease course. GGO was the predominant pattern in week 1, consolidation and mixed pattern in 2 nd week, whereas GGO and reticular patterns in later stages (≥4 weeks).
【저자키워드】 CT, Coronavirus disease 2019 (COVID-19), ground-glass opacity (GGO), 【초록키워드】 COVID-19, hospital, discharge, Retrospective study, Chest CT, persistence, CT scan, Patient, GGO, disease, change, consolidation, RT-PCR test, COVID-19 patient, manifestation, initial symptom, symptom onset, disease course, Stage, material, abnormality, advanced disease, illness duration, later phase, females, feature, initial, Course, analyzed, peaked, the disease, evaluated, facilitate, median, demonstrated, predominant, lung abnormality, the median, 【제목키워드】 Cohort, COVID-19 patient, Radiographic,