Rationale: The clinical data and corresponding dynamic CT findings were investigated in detail to describe the clinical and imaging profiles of COVID-19 pneumonia disease progression. Methods: Forty HCWs with COVID-19 were included in this study and 30 enrolled for imaging assessment. Disease was divided into four stages based on time from onset: stage 1 (1-6 days), stage 2 (7-13 days), stage 3 (14-22 days), and stage 4 (> 22 days). Clinical wand imaging data were analyzed retrospectively. Results: The cohort included 33 female and 7 male cases, with a median age of 40 years. Six had underlying comorbidities. More than half of the cases were nurses (22, 55%). Each stage included 39, 37, 34 and 32 CTs, respectively. Bilateral lesions, multifocal lesions and lesions with GGO pattern occurred in both lower lobes at all stages. The crazy-paving pattern (20, 54%), air bronchogram (13, 35%), and pleural effusion (2, 5%) were the most common CT features in stage 2. Consolidation score peaked in stage 2 whereas total lesions score peaked in stage 3. Conclusions: COVID-19 pneumonia in HCWs has a potential predilection for younger female workers. Stage 2 of COVID-19 pneumonia may be the key period for controlling progression of the disease, and consolidation scores may be an objective reflection of the severity of lung involvement.
【저자키워드】 COVID-19, SARS-CoV-2, Healthcare workers, CT, 【초록키워드】 Pneumonia, severity, lung involvement, Comorbidities, progression, Disease progression, Cohort, clinical, male, female, GGO, consolidation, Nurse, HCW, stage 2, lesion, crazy-paving pattern, stages, profile, Clinical data, median age, lesions, Stage, lower lobe, feature, enrolled, analyzed, occurred, investigated, peaked, the disease, Bilateral, CT finding, with COVID-19, 【제목키워드】 coronavirus disease, Hospitalized, healthcare worker, Characteristics, Chest CT, clinical, feature,