Zoster-Associated Prothrombotic Plasma Exosomes and Increased Stroke Risk

Published on
Journal: Nanoscale
[저자] Andrew N Bubak, Christina Coughlan, Janelle Posey, Anthony J Saviola, Christy S Niemeyer, Serena W R Lewis, Sara Bustos Lopez, Adriana Solano, Stephen K Tyring, Cassidy Delaney, Keith B Neeves, Ravi Mahalingam, Kirk C Hansen, Maria A Nagel
[Category] 대상포진,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1093/infdis/jiac405    
[Article Type] Major Article
[Source] PMC

Compared with plasma exosomes from individuals without herpes zoster (HZ), exosomes from individuals with HZ activate platelets and induce platelet-leukocyte aggregation. These results provide a potential prothrombotic mechanism for the increased risk of stroke associated with HZ.

All Keywords
【저자키워드】 Inflammation, platelet activation, thrombosis, stroke, Exosomes, Varicella zoster virus,