eTOC Blurb Sun et al. combine monophosphoryl lipid A (MPLA) with interferon γ (IFN γ) to reprogram macrophages, activate cytotoxic T cells, suppress tumor growth and metastasis, and enhance chemotherapy response in mice. MPLA and IFNγ are used individually in clinical practice and together represents a previously unexplored approach for eliciting anti-metastatic responses.
All Keywords
【저자키워드】 Breast cancer, Cytotoxic T cells, ovarian cancer, MPLA, IFNγ, tumor-associated macrophages, anti-tumor immune response, metastasis treatment,
【저자키워드】 Breast cancer, Cytotoxic T cells, ovarian cancer, MPLA, IFNγ, tumor-associated macrophages, anti-tumor immune response, metastasis treatment,