Drugs that target protein kinases have had a major impact on the treatment of cancer and now are proving beneficial in numerous immunological diseases. This Review describes their clinical application, with a focus on Janus kinase inhibitors, and how they inform mechanisms of disease and have evolved to improve efficacy and safety.
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【저자키워드】 Molecular medicine, Immunosuppression,
【저자키워드】 Molecular medicine, Immunosuppression,