We propose here that cigarette smoke (CS), in addition to its established genotoxic effects, elicits chronic albeit sub-clinical immune suppression, which is a major contributor to cancer progression. This hypothesis, presented here primarily in the context of bladder cancers (BCs), is applicable to other cancers, including those without a confirmed link to smoking.
All Keywords
【저자키워드】 CD8+ T cells, Immune suppression, immune surveillance, tumor infiltrating lymphocytes,
【저자키워드】 CD8+ T cells, Immune suppression, immune surveillance, tumor infiltrating lymphocytes,