Abstract Background and Purpose : The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death. In response to the COVID-19 pandemic, the Emergency Use Authorization (EUA) approved the use of several vaccines. Because vaccines have been fast-tracked for emergency use, the short and long-term safety profile has been an area of concern. The aim of this paper is to extensively review published literature regarding post-COVID-19 vaccination neurological complications and characterize neuroimaging findings from three case presentations for early diagnosis and treatment. Methods: The analysis includes data from PubMed and Google Scholar. Articles included were retrieved from database inception beginning December 2020 with no language restrictions. Terms used include “SARS-CoV-2”, “post Covid vaccination”, “neurological complications”, “Guillain-barre Syndrome”, “Transverse-myelitis”, “Cerebral Venous Sinus thrombosis”, and “Cerebral hemorrhage”. Results: The literature review yielded several neurological complications post vaccination, including cerebral sinus venous thrombosis, transverse myelitis, Guillain-Barré Syndrome and optic neuritis, to name a few. Patient case presentation findings were consistent with documented results in published literature. Conclusions: We present a case series with a thorough literature review documenting adverse neurological affects following COVID-19 vaccination. Our case presentations and literature review highlight the importance of neuroimaging when diagnosing post-COVID-19 vaccination adverse effects. MRI imaging study is an important tool to be considered in patients presenting with post-COVID-19 vaccination-related unexplained neurological symptoms for accurate diagnosis.
【저자키워드】 COVID-19 vaccination, GBS, Optic neuropathy, transverse myelitis, 【초록키워드】 Treatment, SARS-CoV-2, ARDS, Vaccine, coronavirus, Vaccines, Pneumonia, COVID-19 pandemic, Diagnosis, database, MRI, EUA, adverse effects, early diagnosis, Patient, Venous thrombosis, death, safety profile, Emergency use, acute respiratory distress, Analysis, Emergency, neurological, Neurological complication, Google Scholar, literature review, acute respiratory syndrome, syndrome, article, authorization, diagnosing, term, post vaccination, Affect, Neurological symptom, highlight, Wuhan, China, include, approved, case sery, presenting, mild flu-like symptom, post-COVID-19 vaccination, retrieved, Sinus, 【제목키워드】 review, Neuroimaging, literature, Spectrum, finding, Sery,