Key Points Question What is the long-term efficacy and safety of anti–tumor necrosis factor α agents (anti-TNF) in treating cutaneous sarcoidosis? Findings In this multicenter observational study of 46 patients with sarcoidosis and skin involvement who were treated with anti-TNF, the overall cutaneous response rate was 24% after 3 months, 46% after 6 months, and 79% after 12 months. Eleven (24%) patients stopped anti-TNF because of adverse events, and patients treated for visceral involvement had significantly more infections (48% vs 9.5%), and relapses occurred in half of the patients after discontinuation of anti-TNF. Meaning Anti-TNF agents are effective against cutaneous sarcoidosis with a low infectious rate in patients treated for skin involvement.
Efficacy and Tolerance of Anti–Tumor Necrosis Factor α Agents in Cutaneous Sarcoidosis A French Study of 46 Cases
[Category] 대상포진,
[Article Type] Brief Report
[Source] PMC
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