Background During the initial wave of the COVID-19 epidemic in England, several population characteristics were associated with increased risk of mortality—including, age, ethnicity, income deprivation, care home residence and housing conditions. In order to target control measures and plan for future waves of the epidemic, public health agencies need to understand how these vulnerabilities are distributed across and clustered within communities. Methods We performed a cross-sectional ecological analysis across 6789 small areas in England. We assessed the association between COVID-19 mortality in each area and five vulnerability measures relating to ethnicity, poverty, prevalence of long-term health conditions, living in care homes and living in overcrowded housing. Estimates from multivariable Poisson regression models were used to derive a Small Area Vulnerability Index. Results Four vulnerability measures were independently associated with age-adjusted COVID-19 mortality. Each SD increase in the proportion of the population (1) living in care homes, (2) admitted to hospital in the past 5 years for a long-term health condition, (3) from an ethnic minority background and (4) living in overcrowded housing was associated with a 28%, 19% 8% and 11% increase in age-adjusted COVID-19 mortality rate, respectively. Conclusion Vulnerability to COVID-19 was noticeably higher in the North West, West Midlands and North East regions, with high levels of vulnerability clustered in some communities. Our analysis indicates the communities who will be most at risk from a second wave of the pandemic.
【저자키워드】 public health policy, disease modeling, Health inequalities, 【초록키워드】 COVID-19, public health, pandemic, cross-sectional, hospital, risk, Prevalence, Characteristics, vulnerability, Community, second wave, age, estimate, England, Care, association, COVID-19 epidemic, Analysis, COVID-19 mortality, Deprivation, index, increased risk, measure, North, long-term health conditions, West, agency, Poisson regression model, East, regions, FIVE, the epidemic, multivariable, initial, Result, performed, proportion, indicate, were used, increase in, conditions, Area, ecological, long-term health condition, 【제목키워드】 COVID-19, vulnerability, Community, index, Developing, Area,