Rationale & Objective Studies published from countries with a high prevalence of COVID-19 have found increased incidence and a more severe disease course of coronavirus disease 2019 (COVID-19) in kidney transplant recipients than in the general population. We investigated how the first wave of the COVID-19 pandemic affected the everyday life of kidney transplant recipients in a country with a low infection burden. Study Design Prospective case-control study. Setting & Participants All adult kidney transplant recipients in Norway with a functioning graft and listed in the public phone registry (n = 3,060) and a group of randomly recruited individuals >18 years from the general population (n = 20,000) were invited to participate in the study by an SMS text message. In parallel, all kidney transplant recipients in Norway were invited to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgG from mid-June to October 2020. Predictors The participants were asked to fill out a questionnaire focused on everyday life, travel history, exposure to known COVID-19 cases, and demographics. Analytical Approach Groups were compared with independent tests using 2-sided 0.05 significance levels. Results A total of 1,007 kidney transplant recipients and 4,409 controls answered the questionnaire. The kidney transplant recipients reported being more concerned about SARS-CoV-2 infection (27%) than the control group (7%; P value < 0.001); ie, they behaved more carefully in their everyday life (not going to the grocery store, 5.9% vs 0.9%, P < 0.001; keeping at least 1 meter distance, 16.6% vs 5.8%, P < 0.001). Of the kidney transplant responders, 81% had a SARS-CoV-2 IgG taken; all were negative. Limitations Mortality data is not reliable because of the low number of SARS-CoV-2 infected kidney transplant recipients in Norway. The relatively low questionnaire response rate for kidney transplant recipients is not optimal. Conclusions The questionnaire shows that kidney transplant recipients have behaved more carefully compared with the general population with less social interaction and a very high degree of adherence to governmental advice. Graphical abstract
【저자키워드】 COVID-19, Immunosuppression, Infectious disease, kidney transplant recipient, everyday life behavior, 【초록키워드】 coronavirus disease, SARS-CoV-2, IgG, coronavirus, SARS-COV-2 infection, COVID-19 pandemic, Infection, Prospective, Travel, Control, General population, incidence, group, Norway, First wave, questionnaire, SARS-CoV-2 IgG, kidney transplant, case-control study, COVID-19 cases, demographics, social interaction, acute respiratory syndrome, Abstract, control group, individual, rationale, participant, responders, limitation, severe disease course, SMS, objective, country, setting, independent, Randomly, Result, affected, recruited, reported, investigated, less, asked, fill out, prevalence of COVID-19, 【제목키워드】 survey, Transplant, Behavior, Norway, recipient,