The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I or other apolipoproteins did not. However, there has been no report to elucidate the putative role of apoA-II in the antiviral activity of HDL.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, Glycation, High-density lipoproteins, apoA-I, apoA-II, 【초록키워드】 SARS-COV-2 infection, antiviral activity, Critical, HDL, Apolipoprotein, lipoprotein, high-density, SR-BI, 【제목키워드】 HDL, Apolipoprotein, Importance, Potential,
【저자키워드】 COVID-19, SARS-CoV-2, Glycation, High-density lipoproteins, apoA-I, apoA-II, 【초록키워드】 SARS-COV-2 infection, antiviral activity, Critical, HDL, Apolipoprotein, lipoprotein, high-density, SR-BI, 【제목키워드】 HDL, Apolipoprotein, Importance, Potential,