Purpose To determine fasting plasma glucose and serum 25-hydroxyvitamin D (s-25(OH)D) levels and associations between abnormal fasting plasma glucose levels and inadequate s-25(OH)D levels in individuals of Middle Eastern and Swedish descent. Methods Observational study with individuals without a diabetes diagnosis, 54.5% of Swedish descent and 45.5% of Middle Eastern descent. In total, 830 participants from two primary healthcare centres in Flemingsberg and Jakobsberg, which are southern and northern suburbs, respectively, of Stockholm, Sweden were included in the study. Results Prevalence of inadequate s-25(OH)D levels (at or below 50 nmol/L) was 67.2% among those of Middle Eastern descent and 20.5% among those of Swedish descent ( P < 0.001). S-25(OH)D levels correlated weakly positively with fasting plasma glucose levels (ρ = 0.20, P = 0.002) in individuals of Middle Eastern descent. Being of Middle Eastern descent (OR 6.7, 95% CI 4.3–10.4) and having abnormal fasting plasma glucose (OR 1.8, 95% CI 1.2–2.9) were independent predictors of having inadequate s-25(OH)D levels. Conclusions Healthcare in Sweden should consider testing fasting plasma glucose and s-25(OH)D levels, particularly in individuals of Middle Eastern descent. The unclear relationship between vitamin D and glucose levels warrants investigation. Supplementary Information The online version contains supplementary material available at 10.1007/s40200-023-01226-0. Key points In two primary healthcare centres in low socioeconomic status areas of Sweden, 38.4% of individuals had abnormal fasting plasma glucose levels and 41.8% had inadequate serum 25-hydroxy vitamin D levels. Those of Middle Eastern descent in Sweden had a much higher prevalence (67.2% vs. 20.5%) and odds (Adjusted odds ratio = 6.7) of having inadequate serum 25-hydroxy vitamin D levels than those of Swedish descent. No correlation existed between fasting plasma glucose and serum 25-hydroxy vitamin D levels in those of Swedish descent, and only a weakly positive correlation existed between the levels in those of Middle Eastern descent. Supplementary Information The online version contains supplementary material available at 10.1007/s40200-023-01226-0.
【저자키워드】 diabetes, Glucose, 25-hydroxy vitamin D, immigrant, Middle Eastern,