The severe acute respiratory syndrome coronavirus 2 disease (SARS-CoV-2) is the most severe manifestation of the coronavirus disease 2019 (COVID-19) pandemic. Accruing evidence indicates that the COVID-19 pandemic may have profound deleterious neurological, psychiatric, and psychological outcomes. The number of systematic reviews (SRs) and meta-analyses (MAs) on this topic has grown exponentially. This protocol aims to synthesize all evidence from SRs and MAs on the associations between the COVID-19 pandemic and neuropsychiatric outcomes. The following electronic databases will be systematically searched from inception up to 15 January 2022: PubMed, Embase, APA PsycINFO, and Cochrane Reviews. An umbrella review (UR) of SRs and MAs of observational studies will be conducted. SRs and/or MAs of observational studies examining any direct or indirect association of COVID-19 with the neuropsychiatric outcomes will be deemed eligible for potential inclusion in this UR. The direct associations include the impact on the (1) prognosis of COVID-19 and (2) neuropsychiatric sequelae after COVID-19 infection. The indirect associations include the influence of the COVID-19 pandemic on the (1) treatments and (2) outcomes of neurological and psychiatric conditions associated with the COVID-19 pandemic.
【저자키워드】 COVID-19, SARS-CoV-2, pandemic, mental health, Nervous system diseases, psychiatric diseases, 【초록키워드】 Treatment, coronavirus disease, Meta-analysis, coronavirus, protocol, Prognosis, COVID-19 pandemic, systematic review, outcome, database, observational study, outcomes, COVID-19 infection, Neuropsychiatric, disease, association, Evidence, Deleterious, neurological, Psychiatric, acute respiratory syndrome, Topic, PsycINFO, Inclusion, Psychological outcomes, APA, include, conducted, indicate, searched, eligible, psychiatric condition, 【제목키워드】 review, UMBRELLA,