The objective of this study was to investigate the predictors for new-onset mental disorders among patients with mild to moderate COVID-19 illness during hospitalization. A retrospective cohort study was performed in patients with confirmed COVID-19 admitted to a nationally designated hospital between 1 February and 30 June 2020. Demographic, clinical, psychological assessments, and psychiatric outcomes were obtained from electronic medical record review. Multivariate logistic regression analysis was used to identify predictors of new-onset mental disorders. Among 185 patients, 130 had no history of mental disorders or cognitive impairment at the time of admission. Of 130 patients, 29 (22.3%) were newly diagnosed with mental disorders during hospitalization. The following factors were significantly associated with an increased risk of a psychiatric diagnosis: Charlson comorbidity index core ≥1 (adjusted odds ratio (aOR) = 5.115, 95% confidence interval (CI): 1.737–15.058), length of stay (aOR per 1-day increase = 1.067, 95% CI: 1.035–1.100), and self-reported depressive symptoms at the time of admission (aOR = 5.357, 95% CI: 1.745–16.444). The predictive accuracy of combining these risk factors was relatively high (area under curve = 0.851, 95% CI: 0.778–0.923). These potential risk factors could help to predict the new-onset mental disorder among hospitalized patients with COVID-19.
【저자키워드】 COVID-19, Prognosis, cohort study, Mental disorder, Republic of Korea, 【초록키워드】 Hospitalization, hospital, Comorbidity, outcome, risk factor, Mental Disorders, Moderate COVID-19, Accuracy, Patient, Cognitive impairment, Mild, Psychological, predictor, demographic, Admission, patients, predict, Predictive, retrospective cohort study, Psychiatric, Factor, adjusted odds ratio, Logistic regression analysis, 95% confidence interval, assessments, increased risk, potential risk, help, multivariate, disorder, Mental, depressive symptom, identify, was used, significantly, diagnosed, was performed, hospitalized patient, had no, with COVID-19, 【제목키워드】 development, South Korea,