Immunization of children with inflammatory bowel disease against SARS-CoV-19 infection: A prospective single centre cohort study

Published on
Journal: Vaccine: X
[저자] Dóra Dohos, Anna Karoliny, Eszter Gombos, Éva Rimanóczy, Katalin E. Müller
[Category] update2024,
PMC URL    DOI URL    [DOI] 10.1016/j.jvacx.2023.100374    
[Article Type] article
[Source] pmc

Background Real-world data of children with inflammatory bowel disease (IBD) after SARS-CoV-2 vaccination are needed. Method This prospective, observational study evaluate antibody kinetics of children with IBD 6 months after immunization with COVID-19 mRNA vaccine. Results 24 children with IBD were included, 22 received immunosuppressive treatment. After five weeks the spike protein antibody level was positive in 95% of the cases. After six months all participants had seropositivity results, though the titre was decreasing. Conclusion These data show the effectiveness of SARS-CoV2 immunization and the antibody decay over time, that highlight the importance of booster vaccines.

All Keywords
【저자키워드】 children, immunization, COVID-19 infection, IBD, SARS-CoV2 immunization,