The discovery of novel antiviral materials is important because many infectious diseases are caused by viruses. Silver nanoparticles have demonstrated strong antiviral activity, and graphene is a potential antimicrobial material due to its large surface area, high carrier mobility, and biocompatibility. No studies on the antiviral activity of nanomaterials on non-enveloped viruses have been reported. To investigate the antiviral activity of graphene oxide (GO) sheets and GO sheets with silver particles (GO-Ag) against enveloped and non-enveloped viruses, feline coronavirus (FCoV) with an envelope and infectious bursal disease virus (IBDV) without an envelope were chosen. The morphology and sizes of GO and GO-Ag were characterized by transmission, scanning electron microscopy, and X-ray diffraction. A virus inhibition assay was used to identify the antiviral activity of GO and GO-Ag. Go-Ag inhibited 25% of infection by FCoV and 23% by IBDV, whereas GO only inhibited 16% of infection by FCoV but showed no antiviral activity against the infection by IBDV. Further application of GO and GO-Ag can be considered for personal protection equipment to decrease the transmission of viruses.
【저자키워드】 enveloped virus, Graphene oxide, Feline coronavirus, silver nanoparticle, infectious bursal disease virus, non-enveloped virus, 【초록키워드】 viruses, coronavirus, Antiviral, equipment, Infection, Transmission, Infectious disease, antiviral activity, virus, Particle, Microscopy, virus inhibition, morphology, silver, disease, X-ray diffraction, decrease, non-enveloped viruses, identify, was used, caused, reported, inhibited, characterized, demonstrated, non-enveloped virus, 【제목키워드】 activity, nanocomposite,