A macrophage-targeting peptide was found to selectively home to the inflamed lung, but not healthy organs, in the murine acute lung injury model. Peptide functionalization improves the in vivo biodistribution of a glucocorticoid drug, prednisolone, and thus enhances its therapeutic efficacy and safety when treating acute lung injury.
All Keywords
【저자키워드】 Glucocorticoids, acute lung injury, peptide-guided drug delivery,
【저자키워드】 Glucocorticoids, acute lung injury, peptide-guided drug delivery,