Using a lethal model for β-coronavirus infection, Adams et al. described heterologous protection from disease that was driven by non-neutralizing antibodies through Fc-receptor-dependent mechanisms. These results reveal important protective correlates for inclusion into the design and testing of future pan-coronavirus vaccines.
All Keywords
【저자키워드】 Vaccine development, coronavirus, cross-protection, animal model, Antibody responses, correlates of protection, systems serology, sarbecovirus, pan-coronavirus vaccine, FcR effector function,
【저자키워드】 Vaccine development, coronavirus, cross-protection, animal model, Antibody responses, correlates of protection, systems serology, sarbecovirus, pan-coronavirus vaccine, FcR effector function,