Poly(β-amino ester)s-based nanovehicles: Structural regulation and gene delivery

Chen and colleagues evaluate poly(β-amino) esters (PβAEs) as a promising non-viral gene vector material, discussing their simple synthesis, diverse monomers, and customizable structure for various gene delivery needs. Additionally, the review explores intrinsic structure-effect correlations through rational design and concludes by discussing PβAEs’ applications and future prospects.