Coronavirus (SARS-CoV-2) emerged in China in December 2019 and rapidly caused a global health pandemic. Current evidence seems to suggest a possible link with ecosystem disequilibrium and even air pollution. The primary manifestations affect respiratory and circulatory systems, but neurological features are also being reported through case reports and case series. We summarize neurological symptoms and complications associated with COVID-19. We have searched for original articles published in PubMed/Medline, PubMed Central and Google Scholar using the following keywords: “COVID-19”, “Coronavirus”, “pandemic”, “SARS-COV-2”, “neurology”, “neurological”, “complications” and “manifestations”. We found around 1000 publications addressing the issue of neurological conditions associated with COVID-19 infection. Amongst those, headache and dizziness are the most common reported symptoms followed by encephalopathy and delirium, while the most frequent complications are cerebrovascular accidents, Guillain–Barré syndrome, acute transverse myelitis, and acute encephalitis. Specific symptoms affecting the peripheral nervous system such as hyposmia and dysgeusia are the most common manifestations recorded in the selected studies. Interestingly, it was noted that these kinds of neurological symptoms might precede the typical features, such as fever and cough, in COVID patients. Neurological symptoms and complications associated with COVID-19 should be considered as a part of the clinical features of this novel global pandemic.
【저자키워드】 COVID-19, stroke, Encephalitis, Environment, delirium, Neurological symptoms, 【초록키워드】 SARS-CoV-2, pandemic, Infection, Symptom, cough, headache, Case report, global pandemic, China, Case series, Health, Features, Fever, nervous system, Complication, Encephalopathy, clinical feature, Guillain–Barrè syndrome, Hyposmia, Evidence, neurological, manifestation, Dizziness, Google Scholar, PubMed Central, article, Covid patients, Specific, Affect, ecosystem, feature, cerebrovascular accidents, Neurological symptom, current, selected, caused, reported, condition, searched, affecting, recorded, reported symptom, with COVID-19, 【제목키워드】 manifestation, issue, aspect, New, with COVID-19,