Abstract. Clinical manifestations and complications of SARS-CoV-2 are still emerging and variant. Gastrointestinal (GI) manifestations and complications are hugely under-recognized. The presence of angiotensin converting enzyme-2 receptors in the intestinal enterocytes, the receptors primarily involved in the pathogenesis of COVID-19 pneumonia, maybe the key factor contributing to the pathogenesis of GI manifestations. Ischemic colitis, although the most common ischemic pathology of the GI tract, is relatively rare, occurring as a result of colonic hypoperfusion. The innumerable causes of colonic ischemia are categorized into occlusive and nonocclusive pathologies. Here, we have discussed a case of severe COVID-19 pneumonia, developing ischemic colitis, as a rare GI complication. The cause of ischemia in COVID-19 pneumonia is multifactorial, including hypercoagulable state, coagulopathy leading to thromboembolic complications, and use of vasopressors in severely ill patients with hemodynamic compromise.
【초록키워드】 COVID-19, SARS-CoV-2, pathology, Severe COVID-19 pneumonia, COVID-19 pneumonia, Pathogenesis, Pneumonia, variant, angiotensin converting enzyme, Angiotensin converting enzyme-2, Coagulopathy, clinical manifestations, Gastrointestinal, Complication, Manifestations, receptors, receptor, Pathologies, Hypercoagulable state, GI Tract, Ischemia, hemodynamic, angiotensin, manifestation, hypercoagulable, clinical manifestation, Ischemic colitis, thromboembolic, Vasopressor, vasopressors, Colitis, pathogenesis of COVID-19, key factor, severely ill patients, thromboembolic complications, intestinal enterocytes, occlusive, multifactorial, involved, cause, contributing to, colonic, severely ill patient, 【제목키워드】 COVID-19, Gastrointestinal, Complication, Ischemic,