Structured Graphical Abstract Structured Graphical Abstract The schematic overview over the present study including description of the analysis sample, cross-sectional analyses, and data on clinical outcome, expressed by hazard ratios derived from Cox regression analysis with corresponding 95% confidence intervals and P -values, as well as experimental data on anti-CXCR3 autoantibodies and murine atherosclerosis. aAbs, autoantibodies; ApoE, apolipoprotein E; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; CVRF, cardiovascular risk factors; CXCR3, CXC-motif-chemokine receptor 3; eGFR, estimated glomerular filtration rate; HR, hazard ratio; MACE, major adverse cardiac events (comprising coronary artery disease, myocardial infarction, and cardiac death); ME, membrane extract; NT-proBNP, N-terminal pro-B-type natriuretic peptide; pct, percentile; SD, standard deviation; WTD, western-type diet.
【저자키워드】 Autoimmunity, cardiovascular disease, autoantibodies, Chemokine receptor, G protein-coupled receptor,