The nuclear dot protein 52 (NDP52) is an autophagy receptor known to trigger autophagy following bacterial infection. Here, Cui et al. show that NDP52 also triggers an anti-viral response following hepatitis B virus (HBV) infection. NDP52 forms a tripartite complex with Rab9 and envelope proteins of HBV and targets the virus to Rab9-dependent lysosomal degradation pathway.
All Keywords
【저자키워드】 Virus-host interactions, Hepatitis B virus, Cellular microbiology,
【저자키워드】 Virus-host interactions, Hepatitis B virus, Cellular microbiology,